Score E
Sequences producing significant alignments: (bits) Value
gi|2498952|sp|Q64105|SPRE_MOUSE SEPIAPTERIN REDUCTASE (SPR)... 487 e-137
gi|14714532|gb|AAH10400.1|AAH10400 (BC010400) sepiapterin r... 485 e-136
gi|6755626|ref|NP_035597.1| sepiapterin reductase [Mus musc... 484 e-136
gi|4558172|pdb|1OAA| Mouse Sepiapterin Reductase Complex... 483 e-136
gi|134847|sp|P18297|SPRE_RAT SEPIAPTERIN REDUCTASE (SPR) >g... 437 e-122
gi|206896|gb|AAA42130.1| (M36410) sepiapterin reductase (EC... 434 e-121
gi|4507185|ref|NP_003115.1| sepiapterin reductase (7,8-dihy... 355 3e-97
gi|3885362|dbj|BAA34534.1| (AB017547) sepiapterin reductase... 264 5e-70
gi|2618754|gb|AAC60296.1| (U90880) sepiapterin reductase [T... 197 1e-49
gi|3548968|gb|AAD12760.1| (AF080266) sepiapterin reductase;... 133 1e-30
gi|7689285|gb|AAF67740.1|AF253975_1 (AF253975) sepiapterin ... 118 5e-26
gi|7475814|pir||E70007 sepiapterin reductase homolog yueD -... 94 1e-18
gi|3885364|dbj|BAA34535.1| (AB017548) Sepiapterin Reductase... 93 2e-18
gi|2143520|pir||I64800 sepiapterin reductase (EC 1.1.1.153)... 86 4e-16
gi|2143965|pir||I64799 sepiapterin reductase (EC 1.1.1.153)... 75 7e-13
gi|6322227|ref|NP_012302.1| Yir036cp [Saccharomyces cerevis... 72 6e-12
gi|7290937|gb|AAF46377.1| (AE003444) CG12116 gene product [... 71 9e-12
gi|6322226|ref|NP_012301.1| Yir035cp [Saccharomyces cerevis... 70 1e-11
gi|3219915|sp|O14351|YB45_SCHPO HYPOTHETICAL OXIDOREDUCTASE... 67 1e-10
gi|7290108|gb|AAF45573.1| (AE003419) EG:BACR7A4.14 gene pro... 65 5e-10
gi|14521852|ref|NP_127328.1| 3-OXOACYL-[ACYL-CARRIER-PROTEI... 64 1e-09
gi|10190802|emb|CAB65876.1| (AL109630) /match=(desc:''3-OXO... 64 1e-09
gi|13476756|ref|NP_108325.1| putative dehydrogenase [Mesorh... 63 2e-09
gi|4261779|gb|AAD14079.1|S71376_1 (S71376) sepiapterin redu... 62 5e-09
gi|13815803|gb|AAK42634.1| (AE006848) 3-oxoacyl-(acyl carri... 61 8e-09
gi|6323882|ref|NP_013953.1| Ymr226cp [Saccharomyces cerevis... 61 9e-09
gi|7296706|gb|AAF51985.1| (AE003602) CG11005 gene product [... 61 1e-08
gi|12802725|gb|AAK08072.1|AF325447_1 (AF325447) SDR-like pr... 60 2e-08
gi|14210648|gb|AAK55494.1| (AY033621) putative short-chain ... 60 3e-08
gi|14210658|gb|AAK55499.1| (AY033626) putative short-chain ... 59 3e-08
gi|15004706|ref|NP_149166.1| Oxidoreductase [Clostridium ac... 57 2e-07
gi|7480271|pir||T29125 ketoacyl reductase homolog - Strepto... 57 2e-07
gi|11355759|pir||F82378 oxidoreductase, short-chain dehydro... 57 2e-07
gi|7206794|gb|AAF39953.1| (AC006677) Hypothetical protein R... 56 3e-07
gi|729325|sp|P39483|DHG2_BACME GLUCOSE 1-DEHYDROGENASE II (... 56 3e-07
gi|3913463|sp|O17795|DHBX_CAEEL PUTATIVE STEROID DEHYDROGEN... 56 3e-07
gi|13472648|ref|NP_104215.1| reductase (short chain dehydro... 55 4e-07
gi|12723693|gb|AAK04872.1|AE006311_3 (AE006311) 3-oxoacyl-a... 55 6e-07
gi|13559678|gb|AAK29887.1| (AC024791) Hypothetical protein ... 55 6e-07
gi|3913475|sp|Q17703|DHBV_CAEEL PUTATIVE STEROID DEHYDROGEN... 55 8e-07
gi|7495127|pir||T18829 hypothetical protein C01G12.5 - Caen... 54 9e-07
gi|13559679|gb|AAK29888.1| (AC024791) Hypothetical protein ... 54 1e-06
gi|15228524|ref|NP_186983.1| unknown protein [Arabidopsis t... 54 1e-06
gi|2425123|gb|AAB70845.1| (AF019986) PksB [Dictyostelium di... 54 2e-06
gi|11250506|pir||D82842 oxidoreductase XF0145 [imported] - ... 54 2e-06
gi|7296705|gb|AAF51984.1| (AE003602) CG12171 gene product [... 54 2e-06
gi|729324|sp|P39482|DHG1_BACME GLUCOSE 1-DEHYDROGENASE I (G... 53 2e-06
gi|3913470|sp|O57314|DHBX_ANAPL PUTATIVE STEROID DEHYDROGEN... 53 2e-06
gi|7206785|gb|AAF39944.1| (AC006677) Hypothetical protein R... 53 2e-06
gi|15235621|ref|NP_193054.1| short-chain alcohol dehydrogen... 53 2e-06
gi|729328|sp|P40288|DHG_BACME GLUCOSE 1-DEHYDROGENASE >gi|9... 53 2e-06
gi|11250500|pir||E82748 tropinone reductase XF0913 [importe... 53 2e-06
gi|1711355|sp|Q08632|SDR1_PICAB SHORT-CHAIN TYPE DEHYDROGEN... 53 3e-06
gi|9716967|emb|CAC01636.1| (AL391072) putative ketoreductas... 53 3e-06
gi|8977935|emb|CAB95802.1| (AL359949) putative short chain ... 52 4e-06
gi|12718423|emb|CAC28543.1| (AL513407) putative oxidoreduct... 52 5e-06
gi|7427652|pir||E70027 probable 3-oxoacyl-[acyl-carrier-pro... 52 5e-06
gi|15283302|ref|NP_202457.1| alcohol dehydrogenase [Aquifex... 52 6e-06
gi|11120614|gb|AAG30942.1| (AF314502) glucose dehydrogenase... 52 7e-06
gi|7431006|pir||S76124 hypothetical protein - Synechocystis... 52 7e-06
gi|1731197|sp|Q11150|Y484_MYCTU PUTATIVE OXIDOREDUCTASE RV0... 51 8e-06
gi|7499804|pir||T21330 hypothetical protein F25D1.5 - Caeno... 51 9e-06
gi|13475580|ref|NP_107144.1| probable short-chain dehydroge... 51 1e-05
gi|3913638|sp|O54438|FABG_PSEAE 3-OXOACYL-[ACYL-CARRIER PRO... 50 1e-05
gi|15283629|ref|NP_202784.1| 3-oxoacyl-[acyl-carrier-protei... 50 1e-05
gi|4886772|gb|AAD32035.1|AF093787_3 (AF093787) CylG [Strept... 50 1e-05
gi|7498133|pir||T20301 hypothetical protein D1054.8 - Caeno... 50 1e-05
gi|118561|sp|P07999|DHGB_BACME GLUCOSE 1-DEHYDROGENASE B 50 2e-05
gi|80113|pir||S02299 glucose 1-dehydrogenase (EC 1.1.1.47) ... 50 2e-05
gi|7705925|ref|NP_057370.1| carbonyl reductase [Homo sapien... 50 2e-05
gi|12804319|gb|AAH03018.1|AAH03018 (BC003018) Unknown (prot... 50 2e-05
gi|4139123|gb|AAD03695.1| (AF090422) surface sperm protein ... 50 2e-05
gi|7529640|emb|CAB86467.1| (AL163481) putative short chain ... 50 2e-05
gi|13507282|gb|AAK28547.1| (AF335466) putative oxidoreducta... 50 2e-05
gi|1399845|gb|AAB82041.1| (U59236) unknown [Synechococcus s... 50 2e-05
gi|6671688|ref|NP_031647.1| carbonyl reductase 2 [Mus muscu... 50 3e-05
gi|118559|sp|P10528|DHGA_BACME GLUCOSE 1-DEHYDROGENASE A >g... 50 3e-05
gi|2506151|sp|P31808|YCIK_ECOLI HYPOTHETICAL OXIDOREDUCTASE... 49 4e-05
gi|2226002|emb|CAA74371.1| (Y14043) glucose-1-dehydrogenase... 49 4e-05
gi|15139945|emb|CAC48473.1| (AL603642) putative oxidoreduct... 49 4e-05
gi|3913211|sp|Q21929|CBR2_CAEEL PROBABLE CARBONYL REDUCTASE... 49 4e-05
gi|6680285|ref|NP_032317.1| hydroxysteroid 17-beta dehydrog... 49 5e-05
gi|11351857|pir||G83253 probable short-chain dehydrogenase ... 49 5e-05
gi|12515526|gb|AAG56544.1|AE005380_3 (AE005380) putative ox... 49 5e-05
gi|9789233|gb|AAF98275.1|AF197933_5 (AF197933) beta-ketoacy... 49 5e-05
gi|3182941|sp|Q29529|CBR2_PIG LUNG CARBONYL REDUCTASE [NADP... 49 6e-05
gi|7500118|pir||T21524 hypothetical protein F28H7.2 - Caeno... 48 6e-05
gi|7293522|gb|AAF48896.1| (AE003510) CG7322 gene product [D... 48 7e-05
gi|15229203|ref|NP_187048.1| putative short-chain type dehy... 48 7e-05
gi|7296047|gb|AAF51343.1| (AE003585) CG17711 gene product [... 48 7e-05
gi|80115|pir||S01227 glucose 1-dehydrogenase (EC 1.1.1.47) ... 48 8e-05
gi|7498457|pir||T20490 hypothetical protein F02C12.2 - Caen... 48 8e-05
gi|10174829|dbj|BAB05929.1| (AP001514) 3-oxoacyl-(acyl-carr... 48 9e-05
gi|15159161|gb|AAK89321.1| (AE008273) AGR_L_1487p [Agrobact... 48 9e-05
gi|7495537|pir||T29800 hypothetical protein C06E4.3 - Caeno... 48 9e-05
gi|13278172|gb|AAH03930.1|AAH03930 (BC003930) RIKEN cDNA 11... 48 1e-04
gi|13475878|ref|NP_107448.1| putative oxidoreductase [Mesor... 47 1e-04
gi|10639335|emb|CAC11337.1| (AL445063) probable glucose 1-d... 47 1e-04
gi|7473255|pir||D75522 oxidoreductase, short-chain dehydrog... 47 1e-04
gi|9711279|dbj|BAB07807.1| (AB032242) serine dehydrogenase ... 47 1e-04
Alignments
>gi|2498952|sp|Q64105|SPRE_MOUSE SEPIAPTERIN REDUCTASE (SPR)
gi|1083501|pir||S52110 sepiapterin reductase (EC 1.1.1.153) - mouse
gi|4389157|pdb|1SEP| Mouse Sepiapterin Reductase Complexed With Nadp And Sepiapterin
gi|957230|gb|AAB33611.1| (S77493) sepiapterin reductase, 7,8-dihydropterin:NADP+
oxidoreductase, SPR {EC 1.1.1.153} [mice, Peptide, 261
aa] [Mus sp.]
gi|1094396|prf||2106143A sepiapterin reductase [Mus musculus]
Length = 261
Score = 487 bits (1253), Expect = e-137
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MEADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP 60
MEADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP
Sbjct: 1 MEADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP 60
Query: 61 DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE 120
DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE
Sbjct: 61 DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE 120
Query: 121 VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM 180
VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM
Sbjct: 121 VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM 180
Query: 181 LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ 240
LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ
Sbjct: 181 LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ 240
Query: 241 KLLGLLQKDTFQSGAHVDFYD 261
KLLGLLQKDTFQSGAHVDFYD
Sbjct: 241 KLLGLLQKDTFQSGAHVDFYD 261
>gi|14714532|gb|AAH10400.1|AAH10400 (BC010400) sepiapterin reductase [Mus musculus]
Length = 262
Score = 485 bits (1248), Expect = e-136
Identities = 260/261 (99%), Positives = 260/261 (99%)
Query: 1 MEADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP 60
MEA GLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP
Sbjct: 1 MEAGGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP 60
Query: 61 DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE 120
DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE
Sbjct: 61 DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE 120
Query: 121 VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM 180
VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM
Sbjct: 121 VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM 180
Query: 181 LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ 240
LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ
Sbjct: 181 LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ 240
Query: 241 KLLGLLQKDTFQSGAHVDFYD 261
KLLGLLQKDTFQSGAHVDFYD
Sbjct: 241 KLLGLLQKDTFQSGAHVDFYD 261
>gi|6755626|ref|NP_035597.1| sepiapterin reductase [Mus musculus]
gi|3810565|gb|AAC69364.1| (U78077) sepiapterin reductase [Mus musculus]
Length = 261
Score = 484 bits (1245), Expect = e-136
Identities = 260/261 (99%), Positives = 260/261 (99%)
Query: 1 MEADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP 60
MEA GLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP
Sbjct: 1 MEAGGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP 60
Query: 61 DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE 120
DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE
Sbjct: 61 DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE 120
Query: 121 VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM 180
VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM
Sbjct: 121 VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM 180
Query: 181 LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ 240
LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ
Sbjct: 181 LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ 240
Query: 241 KLLGLLQKDTFQSGAHVDFYD 261
KLLGLLQKDTFQSGAHVDFYD
Sbjct: 241 KLLGLLQKDTFQSGAHVDFYD 261
>gi|4558172|pdb|1OAA| Mouse Sepiapterin Reductase Complexed With Nadp And Oxaloacetate
gi|4699613|pdb|1NAS| Sepiapterin Reductase Complexed With N-Acetyl Serotonin
Length = 259
Score = 483 bits (1243), Expect = e-136
Identities = 259/259 (100%), Positives = 259/259 (100%)
Query: 3 ADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDL 62
ADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDL
Sbjct: 1 ADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDL 60
Query: 63 KVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVN 122
KVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVN
Sbjct: 61 KVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVN 120
Query: 123 NYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLY 182
NYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLY
Sbjct: 121 NYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLY 180
Query: 183 QVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKL 242
QVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKL
Sbjct: 181 QVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKL 240
Query: 243 LGLLQKDTFQSGAHVDFYD 261
LGLLQKDTFQSGAHVDFYD
Sbjct: 241 LGLLQKDTFQSGAHVDFYD 259
>gi|134847|sp|P18297|SPRE_RAT SEPIAPTERIN REDUCTASE (SPR)
gi|1083797|pir||A36024 sepiapterin reductase (EC 1.1.1.153) - rat
Length = 262
Score = 437 bits (1124), Expect = e-122
Identities = 231/261 (88%), Positives = 245/261 (93%)
Query: 1 MEADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQP 60
ME LGCAVCVLTGASRGFGRALAPQLA LLSPGSV+L+SARS+SMLRQLKEEL QQP
Sbjct: 1 MEGGRLGCAVCVLTGASRGFGRALAPQLAGLLSPGSVLLLSARSDSMLRQLKEELCTQQP 60
Query: 61 DLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE 120
L+VVLAAADLGTE+GVQ+LLSAVRELPRPE LQRLLLINNA TLGDVSKGFLN+NDLAE
Sbjct: 61 GLQVVLAAADLGTESGVQQLLSAVRELPRPERLQRLLLINNAGTLGDVSKGFLNINDLAE 120
Query: 121 VNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDM 180
VNNYWALNLTSMLCLT+GTLNAF +SPGLSKTVVNISSLCALQP+KGWGLYCAGKAARDM
Sbjct: 121 VNNYWALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDM 180
Query: 181 LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQ 240
LYQVLA EEPSVRVLSYAPGPLD +MQQLARETS DPELRS+LQKL S+G LVDCGTSAQ
Sbjct: 181 LYQVLAVEEPSVRVLSYAPGPLDTNMQQLARETSMDPELRSRLQKLNSEGELVDCGTSAQ 240
Query: 241 KLLGLLQKDTFQSGAHVDFYD 261
KLL LLQ+DTFQSGAHVDFYD
Sbjct: 241 KLLSLLQRDTFQSGAHVDFYD 261
>gi|206896|gb|AAA42130.1| (M36410) sepiapterin reductase (EC 1.1.1.153) [Rattus norvegicus]
Length = 259
Score = 434 bits (1117), Expect = e-121
Identities = 229/256 (89%), Positives = 243/256 (94%)
Query: 6 LGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVV 65
LGCAVCVLTGASRGFGRALAPQLA LLSPGSV+L+SARS+SMLRQLKEEL QQP L+VV
Sbjct: 3 LGCAVCVLTGASRGFGRALAPQLAGLLSPGSVLLLSARSDSMLRQLKEELCTQQPGLQVV 62
Query: 66 LAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYW 125
LAAADLGTE+GVQ+LLSAVRELPRPE LQRLLLINNA TLGDVSKGFLN+NDLAEVNNYW
Sbjct: 63 LAAADLGTESGVQQLLSAVRELPRPERLQRLLLINNAGTLGDVSKGFLNINDLAEVNNYW 122
Query: 126 ALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVL 185
ALNLTSMLCLT+GTLNAF +SPGLSKTVVNISSLCALQP+KGWGLYCAGKAARDMLYQVL
Sbjct: 123 ALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDMLYQVL 182
Query: 186 AAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGL 245
A EEPSVRVLSYAPGPLD +MQQLARETS DPELRS+LQKL S+G LVDCGTSAQKLL L
Sbjct: 183 AVEEPSVRVLSYAPGPLDTNMQQLARETSMDPELRSRLQKLNSEGELVDCGTSAQKLLSL 242
Query: 246 LQKDTFQSGAHVDFYD 261
LQ+DTFQSGAHVDFYD
Sbjct: 243 LQRDTFQSGAHVDFYD 258
>gi|4507185|ref|NP_003115.1| sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase);
Sepiapterin reductase [Homo sapiens]
gi|11429089|ref|XP_002347.1| sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
[Homo sapiens]
gi|464801|sp|P35270|SPRE_HUMAN SEPIAPTERIN REDUCTASE (SPR)
gi|88585|pir||JQ1176 sepiapterin reductase (EC 1.1.1.153) - human
gi|338021|gb|AAA60314.1| (M76231) sepiapterin reductase [Homo sapiens]
Length = 261
Score = 355 bits (910), Expect = 3e-97
Identities = 192/257 (74%), Positives = 224/257 (86%)
Query: 5 GLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKV 64
GLG AVC+LTGASRGFGR LAP LA LLSPGSV+++SAR++ LRQL+ ELGA++ L+V
Sbjct: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63
Query: 65 VLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNY 124
V ADLG EAG+Q+LL A+RELPRP+GLQRLLLINNA +LGDVSKGF++++D +VNNY
Sbjct: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123
Query: 125 WALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQV 184
WALNLTSMLCLTS L AF DSPGL++TVVNISSLCALQP+KGW LYCAGKAARDML+QV
Sbjct: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183
Query: 185 LAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLG 244
LA EEP+VRVL+YAPGPLD DMQQLARETS DP++R LQ+LK+ G LVDC SAQKLL
Sbjct: 184 LALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243
Query: 245 LLQKDTFQSGAHVDFYD 261
LL+KD F+SGAHVDFYD
Sbjct: 244 LLEKDEFKSGAHVDFYD 260
>gi|3885362|dbj|BAA34534.1| (AB017547) sepiapterin reductase [Homo sapiens]
Length = 198
Score = 264 bits (675), Expect = 5e-70
Identities = 146/195 (74%), Positives = 172/195 (87%)
Query: 5 GLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKV 64
GLG AVC+LTGASRGFGR LAP LA LLSPGSV+++SAR++ LRQL+ ELGA++ L+V
Sbjct: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63
Query: 65 VLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNY 124
V ADLG EAG+Q+LL A+RELPRP+GLQRLLLINNA +LGDVSKGF++++D +VNNY
Sbjct: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123
Query: 125 WALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQV 184
WALNLTSMLCLTS L AF DSPGL++TVVNISSLCALQP+KGW LYCAGKAARDML+QV
Sbjct: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183
Query: 185 LAAEEPSVRVLSYAP 199
LA EEP+VRVL+YAP
Sbjct: 184 LALEEPNVRVLNYAP 198
>gi|2618754|gb|AAC60296.1| (U90880) sepiapterin reductase [Takifugu rubripes]
Length = 256
Score = 197 bits (500), Expect = 1e-49
Identities = 120/259 (46%), Positives = 164/259 (62%), Gaps = 20/259 (7%)
Query: 6 LGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEEL----GAQQPD 61
LG +CV+TGASRG GRA+A ++ L+ PGSV+L+ ARSE++L++LKEEL G QP
Sbjct: 12 LGRCLCVITGASRGLGRAMAREVCGLMKPGSVLLLVARSETLLQELKEELRGLTGTAQPA 71
Query: 62 LKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEV 121
++ V A DL GV + R+ + +LLINNA +LGD+SK F + +DL EV
Sbjct: 72 VRCV--AVDLSAAGGVNEAVEVARQEAGTDP-DHVLLINNAGSLGDISK-FSSFSDLNEV 127
Query: 122 NNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDML 181
N+Y +LN+ S L L +G L F PGL +VVNISSL A+Q W LYC KA R M+
Sbjct: 128 NSYLSLNVRSALALNAGMLRVFPSRPGLRWSVVNISSLFAVQALPNWALYCTAKADRKMM 187
Query: 182 YQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQK 241
+ VLA EEP+V+VLSY+PGP+D +MQ KD + +L +K L+ C A K
Sbjct: 188 FSVLADEEPNVKVLSYSPGPMDTEMQ-------KDIQ---RLTGIKHH--LIPCKEPAAK 235
Query: 242 LLGLLQKDTFQSGAHVDFY 260
L+ LL + F SG+H+DF+
Sbjct: 236 LMKLLLVNEFASGSHLDFF 254
>gi|3548968|gb|AAD12760.1| (AF080266) sepiapterin reductase; SR [Drosophila melanogaster]
gi|6006815|gb|AAF00619.1|AF167284_1 (AF167284) sepiapterin reductase [Drosophila melanogaster]
gi|7290936|gb|AAF46376.1| (AE003444) Sptr gene product [Drosophila melanogaster]
Length = 261
Score = 133 bits (335), Expect = 1e-30
Identities = 81/253 (32%), Positives = 138/253 (54%), Gaps = 7/253 (2%)
Query: 12 VLTGASRGFGRALAPQLA-RLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAAD 70
++TGASRG GR A QLA R+ + GS++ + R++++L++ K E+ A PDL V + +
Sbjct: 10 LVTGASRGIGREFAQQLAKRIKAEGSMVTLLGRNQTLLQESKAEIVATVPDLSVQTYSLE 69
Query: 71 LGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNLT 130
L T A + + +R ++I+NA T+GD SK + D + Y+ N+
Sbjct: 70 LET-AKTEDFTKILEASGGKNNFERAIVIHNAGTVGDTSKRAKEIGDTDFLQRYYHSNVF 128
Query: 131 SMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAEEP 190
S + L + F+ G+ K VVN+S+L A+ P YC KAAR+M ++VLA EE
Sbjct: 129 SAISLNCEFMRVFK---GIPKLVVNLSTLAAIAPISSMAHYCTVKAAREMYFRVLATEES 185
Query: 191 S--VRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGLLQK 248
+ VL+YAPG +D M + + DP + + ++ + ++ + ++ + +L+
Sbjct: 186 AEDTLVLNYAPGVIDTQMTVQVQREAHDPAVVAMFREQRESKTMLTPAQTTERFIKVLEA 245
Query: 249 DTFQSGAHVDFYD 261
F+SG HVD+ D
Sbjct: 246 FKFKSGDHVDYRD 258
>gi|7689285|gb|AAF67740.1|AF253975_1 (AF253975) sepiapterin reductase [Dictyostelium discoideum]
Length = 265
Score = 118 bits (295), Expect = 5e-26
Identities = 81/263 (30%), Positives = 132/263 (49%), Gaps = 14/263 (5%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVS----ARSESMLRQLKEELGAQQPDLKVV 65
+ ++TGAS+GFG+A+A ++ + +P L+ ARS L+ KE + + KV+
Sbjct: 3 LAIVTGASKGFGKAIAQEIVK-CNPNKNQLIDLVLFARSLDGLKSTKESIETISTNAKVI 61
Query: 66 -LAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNY 124
L + D+ V+ +V E + E ++ NN TL + + + +D +
Sbjct: 62 DLQSLDMSNIPDVELKFKSVLENIKWEEYSKICFFNNHGTLYHLGR-IEDFSDFKNIQKD 120
Query: 125 WALNLTSMLCLTS---GTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDML 181
N TS + TS L T+VN SSLCA++ + W LYC+ +A RDM
Sbjct: 121 NDTNTTSFVVTTSLLVKKLKELGSQYSSEVTIVNSSSLCAIKAFPTWSLYCSSRAYRDMF 180
Query: 182 YQVLAAE---EPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTS 238
+Q L+ E +VL+Y+ G LD DMQ RE + + +S LK+DG L++ S
Sbjct: 181 FQALSLEYKLNDKFKVLNYSLGVLDTDMQSQVREECSEDD-KSFYVGLKNDGKLINPNRS 239
Query: 239 AQKLLGLLQKDTFQSGAHVDFYD 261
A L+ F++G+H+D+YD
Sbjct: 240 ASICSNLVYSHKFETGSHLDYYD 262
>gi|7475814|pir||E70007 sepiapterin reductase homolog yueD - Bacillus subtilis
gi|2635679|emb|CAB15172.1| (Z99120) similar to sepiapterin reductase [Bacillus subtilis]
Length = 243
Score = 94.4 bits (233), Expect = 1e-18
Identities = 81/244 (33%), Positives = 122/244 (49%), Gaps = 22/244 (9%)
Query: 12 VLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAADL 71
++TGAS+G G+A+A Q L G + +R+++ + K L Q DL + A
Sbjct: 5 IITGASKGLGQAIALQ---ALEKGHEVHALSRTKTDVSHKK--LTQHQIDLINLEEA--- 56
Query: 72 GTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNLTS 131
E + LLS++ + R G+ LINNA + + + L E+ ++ LNLT+
Sbjct: 57 --EQQFETLLSSI-DSDRYSGIT---LINNAGMVTPIKRA--GEASLDELQRHYQLNLTA 108
Query: 132 MLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLA----A 187
+ L+ F G KTVVNI+S A PYKGW YC+ KA DM +
Sbjct: 109 PVLLSQLFTKRFASYSG-KKTVVNITSGAAKNPYKGWSAYCSSKAGLDMFTRTFGFEQED 167
Query: 188 EEPSVRVLSYAPGPLDNDMQQLARETS-KDPELRSKLQKLKSDGALVDCGTSAQKLLGLL 246
EE V ++S++PG +D +MQ + R +S KD + +KL G+L A LL LL
Sbjct: 168 EELPVNMISFSPGVMDTEMQAVIRSSSKKDFHHIERFRKLNETGSLRSPDFIAGTLLSLL 227
Query: 247 QKDT 250
+K T
Sbjct: 228 EKGT 231
>gi|3885364|dbj|BAA34535.1| (AB017548) Sepiapterin Reductase [Homo sapiens]
Length = 62
Score = 93.2 bits (230), Expect = 2e-18
Identities = 45/61 (73%), Positives = 51/61 (82%)
Query: 201 PLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGLLQKDTFQSGAHVDFY 260
PLD DMQQLARETS DP++R LQ+LK+ G LVDC SAQKLL LL+KD F+SGAHVDFY
Sbjct: 1 PLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFY 60
Query: 261 D 261
D
Sbjct: 61 D 61
>gi|2143520|pir||I64800 sepiapterin reductase (EC 1.1.1.153) - mouse (fragment)
Length = 47
Score = 85.5 bits (210), Expect = 4e-16
Identities = 47/47 (100%), Positives = 47/47 (100%)
Query: 209 LARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGLLQKDTFQSGA 255
LARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGLLQKDTFQSGA
Sbjct: 1 LARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGLLQKDTFQSGA 47
>gi|2143965|pir||I64799 sepiapterin reductase (EC 1.1.1.153) - rat (fragment)
gi|266078|gb|AAB25506.1| (S55545) sepiapterin reductase [Rattus sp.]
Length = 47
Score = 74.7 bits (182), Expect = 7e-13
Identities = 40/47 (85%), Positives = 43/47 (91%)
Query: 209 LARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGLLQKDTFQSGA 255
LARETS DPELRS+LQKL S+G LVDCGTSAQKLL LLQ+DTFQSGA
Sbjct: 1 LARETSMDPELRSRLQKLNSEGELVDCGTSAQKLLSLLQRDTFQSGA 47
>gi|6322227|ref|NP_012302.1| Yir036cp [Saccharomyces cerevisiae]
gi|731923|sp|P40580|YIV6_YEAST HYPOTHETICAL OXIDOREDUCTASE IN LYS1-HYR1 INTERGENIC REGION
gi|626387|pir||S48498 oxidoreductase homolog YIR036c - yeast (Saccharomyces cerevisiae)
gi|557842|emb|CAA86196.1| (Z38061) orf, len: 263, CAI: 0.12, similar to orf (32877..33641)
and BA71_EUBSP P07914 7-ALPHA -HYDROXYSTEROID
DEHYDROGENASE [Saccharomyces cerevisiae]
Length = 263
Score = 71.6 bits (174), Expect = 6e-12
Identities = 73/249 (29%), Positives = 117/249 (46%), Gaps = 22/249 (8%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69
V ++TGASRG G L + V V AR+E+ L+ L+ E GA K V
Sbjct: 4 VILITGASRGIGLQLVKTVIEEDDECIVYGV-ARTEAGLQSLQREYGAD----KFVYRVL 58
Query: 70 DLGTEAGVQRLLSAVREL-PRPEGLQRLLLINNAATLGDVSKGFLNVN---DLAEVNNYW 125
D+ + ++ L+ +R+ + +G ++ NA L V K N D+ + +
Sbjct: 59 DITDRSRMEALVEEIRQKHGKLDG-----IVANAGMLEPV-KSISQSNSEHDIKQWERLF 112
Query: 126 ALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVL 185
+N S++ L + L + SP + +V +SS +++PY GW Y KAA + +
Sbjct: 113 DVNFFSIVSLVALCLPLLKSSPFVG-NIVFVSSGASVKPYNGWSAYGCSKAALNHFAMDI 171
Query: 186 AAEEPS--VRVLSYAPGPLDNDMQQLARET----SKDPELRSKLQKLKSDGALVDCGTSA 239
A+EEPS VR + APG +D MQ+ RET P+ + +L +L+D A
Sbjct: 172 ASEEPSDKVRAVCIAPGVVDTQMQKDIRETLGPQGMTPKALERFTQLYKTSSLLDPKVPA 231
Query: 240 QKLLGLLQK 248
L L+ K
Sbjct: 232 AVLAQLVLK 240
>gi|7290937|gb|AAF46377.1| (AE003444) CG12116 gene product [Drosophila melanogaster]
Length = 273
Score = 70.9 bits (172), Expect = 9e-12
Identities = 70/262 (26%), Positives = 123/262 (46%), Gaps = 19/262 (7%)
Query: 12 VLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQ--QPDLKVVLAAA 69
VL+G+S G++LA + R L+ GS+ L+ + LR+L+ L ++ ++KV +
Sbjct: 15 VLSGSSNPLGQSLALEFCRRLATGSLALILDEDQEQLRELENHLRSELKTENVKVTIGKL 74
Query: 70 DLGTEAGVQRLLSAVREL----PRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYW 125
D GVQ + A+ + + +R ++++N + L + Y
Sbjct: 75 DKDHSNGVQLMEQALMDNFMADKDNQRFERSIILHNEGKAA--THMLLEPQSDDDWKAYV 132
Query: 126 ALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVL 185
L + + L L + + + K VN++S ++P GL C+ K ARDM ++ +
Sbjct: 133 QQQLYAPVALNQTWLQS-KHLERVEKLAVNVTSSLMVRPLVHAGLLCSCKRARDMYFRAM 191
Query: 186 AAEEP--SVRVLSYAPGPLDNDMQQL----ARETSKDPELRSKLQKLKSDGALVDCGTSA 239
AAEE V VLS++PG +D Q R T D +L +L + +
Sbjct: 192 AAEEYRFGVHVLSFSPGLMDTHEGQCDVNGNRITPADLIATKQLLQLPR----IKPCQAT 247
Query: 240 QKLLGLLQKDTFQSGAHVDFYD 261
KL+ +L++ +F SG VD+YD
Sbjct: 248 LKLINILEEISFVSGHDVDYYD 269
>gi|6322226|ref|NP_012301.1| Yir035cp [Saccharomyces cerevisiae]
gi|731922|sp|P40579|YIV5_YEAST HYPOTHETICAL OXIDOREDUCTASE IN LYS1-HYR1 INTERGENIC REGION
gi|626386|pir||S48497 oxidoreductase homolog YIR035c - yeast (Saccharomyces cerevisiae)
gi|557841|emb|CAA86195.1| (Z38061) orf, len 254, CAI: 0.24, 52.1% similar to orf
complement(33925..34716), similar to DHII_HUMAN P28845
CORTICOSTEROID 11-BETA-DEHYDROGENASE [Saccharomyces
cerevisiae]
Length = 254
Score = 70.5 bits (171), Expect = 1e-11
Identities = 69/238 (28%), Positives = 115/238 (47%), Gaps = 27/238 (11%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69
V ++TG SRG G+++ L L +V+ ARSE+ L++LKE+ G +
Sbjct: 4 VILVTGVSRGIGKSIVDVLFS-LDKDTVVYGVARSEAPLKKLKEKYGD-----RFFYVVG 57
Query: 70 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNY---W 125
D+ ++ +++L++A +G ++ L+ NA L V NVN++ +VN + +
Sbjct: 58 DITEDSVLKQLVNAA-----VKGHGKIDSLVANAGVLEPVQ----NVNEI-DVNAWKKLY 107
Query: 126 ALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVL 185
+N S++ L L + + G VV +SS + WG Y + KAA + L
Sbjct: 108 DINFFSIVSLVGIALPELKKTNG---NVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTL 164
Query: 186 AAEEPSVRVLSYAPGPLDNDMQQLARE----TSKDPELRSKLQKLKSDGALVDCGTSA 239
A EE V+ ++ APG +D DMQ RE +S E + LK + L+D A
Sbjct: 165 ANEERQVKAIAVAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPA 222
>gi|3219915|sp|O14351|YB45_SCHPO HYPOTHETICAL OXIDOREDUCTASE C30D10.05C IN CHROMOSOME II
gi|7493400|pir||T40191 short chain dehydrogenase - fission yeast (Schizosaccharomyces
pombe)
gi|2276354|emb|CAB10800.1| (Z97992) short chain dehydrogenase [Schizosaccharomyces pombe]
Length = 247
Score = 67.4 bits (163), Expect = 1e-10
Identities = 65/228 (28%), Positives = 107/228 (46%), Gaps = 23/228 (10%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69
V +LTG+S+G G A A L + V A S S+ +L E L Q PD V
Sbjct: 8 VILLTGSSKGIGLATAEALQKKAK------VIAVSRSLTPEL-ETLLIQNPD-SFVHVKG 59
Query: 70 DLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNL 129
D+ TE G + +A+++ + + +I NA L ++K + D+ E + +N
Sbjct: 60 DV-TEVGKASIETAIKKFGKLDS-----VILNAGVLEPIAK--IADADINEWRKLFDINF 111
Query: 130 TSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAEE 189
S++ + + + G T+V +SS A++ + W YC KAA +ML L +EE
Sbjct: 112 FSVVETVKYAIPHLRKTKG---TIVIVSSGAAVRVFPAWAAYCCSKAAINMLVMNLGSEE 168
Query: 190 PSVRVLSYAPGPLDNDMQQLARETSKDPEL----RSKLQKLKSDGALV 233
P + ++ PG +D MQ R S + + ++LK+ G LV
Sbjct: 169 PDIMSVAVRPGVVDTPMQVSIRNDSNKEAMGGDTHNFFKELKTSGQLV 216
>gi|7290108|gb|AAF45573.1| (AE003419) EG:BACR7A4.14 gene product [Drosophila melanogaster]
Length = 270
Score = 65.1 bits (157), Expect = 5e-10
Identities = 61/193 (31%), Positives = 91/193 (46%), Gaps = 21/193 (10%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69
V ++TGAS G G A+A LAR G+ + + R+ + L K+ L Q + +V+A
Sbjct: 7 VVIVTGASSGIGAAIAQVLAR---EGATLALVGRNVANLEATKKSLKGTQAE--IVVADV 61
Query: 70 DLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNL 129
+A VQ+ L+ + +L+NNA LG KG L D+ E + NL
Sbjct: 62 TKDADAIVQQTLAKFGRID--------VLVNNAGILG---KGGLIDLDIEEFDAVLNTNL 110
Query: 130 TSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE- 188
++ LT L + G VVN+SS ++P+ G Y KAA D +++A E
Sbjct: 111 RGVILLTKAVLPHLLKTKG---AVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEM 167
Query: 189 -EPSVRVLSYAPG 200
VRV S PG
Sbjct: 168 APQGVRVNSVNPG 180
>gi|14521852|ref|NP_127328.1| 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [Pyrococcus abyssi]
gi|7431024|pir||H75014 3-oxoacyl-[acyl-carrier-protein] reductase PAB1085 - Pyrococcus
abyssi (strain Orsay)
gi|5459072|emb|CAB50558.1| (AJ248288) 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [Pyrococcus
abyssi]
Length = 240
Score = 63.9 bits (154), Expect = 1e-09
Identities = 70/242 (28%), Positives = 111/242 (44%), Gaps = 26/242 (10%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69
V ++TGASRG GRA+A +LA+ G ++++ RS + EEL +Q ++ +L A
Sbjct: 7 VALITGASRGIGRAIAIELAK---RGVNVVINYRSNEEEAKKTEEL-CRQYGVETLLVKA 62
Query: 70 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWALN 128
D+ V+ ++ V + R+ +LINNA LG +K L V D E + ++N
Sbjct: 63 DVSNREEVREMVKKV-----IDKFGRIDILINNAGILGK-TKDPLEVTD-EEWDRVISVN 115
Query: 129 LTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 188
L +T L + +VNI+S+ Y A K L LA
Sbjct: 116 LKGAFIVTQEVLRYMKKG-----KIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLARH 170
Query: 189 -EPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGLLQ 247
P++ V + APGP+D DM E++ L+KL G + A ++ LL+
Sbjct: 171 LAPNILVNAVAPGPVDTDMLS--------SEMKEMLKKLSLTGDIAKPSEVAHAVIFLLE 222
Query: 248 KD 249
D
Sbjct: 223 ND 224
>gi|10190802|emb|CAB65876.1| (AL109630) /match=(desc:''3-OXOACYL-[ACYL-CARRIER PROTEIN]
REDUCTASE (EC 1.1.1.100) (3-KETOACYL- ACYL CARRIER
PROTEIN REDUCTASE)'', species:''Escherichia coli'',
ranges:(query:124808..124897,
target:SWISS-PROT::P25716:30..1, score:''84.00''),
(query:12>
Length = 251
Score = 63.5 bits (153), Expect = 1e-09
Identities = 61/193 (31%), Positives = 91/193 (46%), Gaps = 21/193 (10%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69
V ++TGAS G G A+A LAR G+ + + R+ + L K+ L Q + +V+A
Sbjct: 7 VVIVTGASSGIGAAIAQVLAR---EGATLALVGRNVANLEATKKSLKGTQAE--IVVADV 61
Query: 70 DLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNL 129
+A VQ+ L+ + +L+NNA LG KG L D+ E + NL
Sbjct: 62 TKDADAIVQQTLAKFGRID--------VLVNNAGILG---KGGLIDLDIEEFDAVLNTNL 110
Query: 130 TSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE- 188
++ LT L + G VVN+SS ++P+ G Y KAA D +++A E
Sbjct: 111 RGVILLTKAVLPHLLKTKG---AVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEM 167
Query: 189 -EPSVRVLSYAPG 200
VRV S PG
Sbjct: 168 APQGVRVNSVNPG 180
>gi|13476756|ref|NP_108325.1| putative dehydrogenase [Mesorhizobium loti]
gi|14027517|dbj|BAB53786.1| (AP003013) putative dehydrogenase [Mesorhizobium loti]
Length = 257
Score = 63.2 bits (152), Expect = 2e-09
Identities = 63/201 (31%), Positives = 100/201 (49%), Gaps = 18/201 (8%)
Query: 12 VLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAADL 71
++TG S G G A+A LS G+ +L+ R + L +++L A V ++ADL
Sbjct: 9 LVTGGSDGIGLAIAEA---FLSEGADVLIVGRDAAKLEAARQKLAALGQAGAVETSSADL 65
Query: 72 GTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNLTS 131
T GV ++ V+E RP + INNA V F +V++ A+ + +ALN+ +
Sbjct: 66 ATSLGVATVVEQVKETGRPLDIP----INNAGVADLVP--FESVSE-AQFQHSFALNVAA 118
Query: 132 MLCLTSGTLNAFQDSPGLSKTVVNISSLCA--LQPYKGWGLYCAGKAARDMLYQVLAAE- 188
LT G L F G +++NISS A + P + +Y K A + L + LA E
Sbjct: 119 AFFLTQGLLPHF----GAGASIINISSYFARKMIPKRPSSVYSLSKGALNSLTRSLAFEL 174
Query: 189 -EPSVRVLSYAPGPLDNDMQQ 208
+RV + APG +D M++
Sbjct: 175 GPRGIRVNAIAPGTVDTAMRR 195
>gi|4261779|gb|AAD14079.1|S71376_1 (S71376) sepiapterin reductase [Homo sapiens]
Length = 47
Score = 62.0 bits (149), Expect = 5e-09
Identities = 32/47 (68%), Positives = 38/47 (80%)
Query: 209 LARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGLLQKDTFQSGA 255
LARETS DP++R LQ+LK+ G LVDC SAQKLL LL+KD F+SGA
Sbjct: 1 LARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGA 47
>gi|13815803|gb|AAK42634.1| (AE006848) 3-oxoacyl-(acyl carrier protein) reductase (fabG-7)
[Sulfolobus solfataricus]
Length = 252
Score = 61.2 bits (147), Expect = 8e-09
Identities = 64/197 (32%), Positives = 102/197 (51%), Gaps = 26/197 (13%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSA--RSESM---LRQLKEELGAQQPDLKV 64
V V+TG+ RG GRA+A +LA+ GS+++V+A R++ M ++ +KE G +
Sbjct: 8 VVVVTGSGRGIGRAIAVRLAK---EGSLVVVNAKKRADEMNETIKIIKENGG------EA 58
Query: 65 VLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNY 124
+ AD+ T G + L A + R +LINNA LG S FLNV+D ++ +
Sbjct: 59 IGILADVSTREGCETLAKATIDRYRVAD----ILINNAG-LGLFSP-FLNVDD-KLLDKH 111
Query: 125 WALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQV 184
+ + S++ + +D +VNI+S+ + P G +Y A KAA L +
Sbjct: 112 ISTDFKSVVYCSQSLAKEMRD----GGAIVNIASVAGVSPAYGLSIYGAMKAAVIALTKY 167
Query: 185 LAAE-EPSVRVLSYAPG 200
LA E P +RV + APG
Sbjct: 168 LALELAPKIRVNAIAPG 184
>gi|6323882|ref|NP_013953.1| Ymr226cp [Saccharomyces cerevisiae]
gi|2492763|sp|Q05016|YM71_YEAST HYPOTHETICAL OXIDOREDUCTASE IN MRPL44-MTF1 INTERGENIC REGION
gi|1362394|pir||S57593 hypothetical protein YMR226c - yeast (Saccharomyces cerevisiae)
gi|887607|emb|CAA90197.1| (Z49939) unknown [Saccharomyces cerevisiae]
Length = 267
Score = 61.2 bits (147), Expect = 9e-09
Identities = 57/206 (27%), Positives = 100/206 (47%), Gaps = 12/206 (5%)
Query: 3 ADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDL 62
A+ L ++TGAS G G+A A + + ++++AR L +LK+ + + P+
Sbjct: 8 AERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNA 67
Query: 63 KVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAA-TLGDVSKGFLNVNDLAEV 121
KV +A D+ T+A +++ + LP+ E +L+NNA LG G + D+ +V
Sbjct: 68 KVHVAQLDI-TQA--EKIKPFIENLPQ-EFKDIDILVNNAGKALGSDRVGQIATEDIQDV 123
Query: 122 NNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDML 181
+ N+T+++ +T L FQ S +VN+ S+ Y +YCA K A
Sbjct: 124 ---FDTNVTALINITQAVLPIFQAKN--SGDIVNLGSIAGRDAYPTGSIYCASKFAVGAF 178
Query: 182 YQVLAAE--EPSVRVLSYAPGPLDND 205
L E +RV+ APG ++ +
Sbjct: 179 TDSLRKELINTKIRVILIAPGLVETE 204
>gi|7296706|gb|AAF51985.1| (AE003602) CG11005 gene product [Drosophila melanogaster]
Length = 1639
Score = 60.8 bits (146), Expect = 1e-08
Identities = 60/204 (29%), Positives = 98/204 (47%), Gaps = 22/204 (10%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69
V ++TGAS G G + A LA+L G ++++ R+E L++ + + A + L A
Sbjct: 1390 VIIVTGASSGIGASAAVHLAKL---GGLLVIVGRNEEKLKETADNIVAAGGATPLEL-QA 1445
Query: 70 DLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNL 129
D+ EA VQ+++ A L + + +L+NNA L G + L + + N+
Sbjct: 1446 DMTKEAEVQQIVGAT--LAKHGRID--VLVNNAGIL---ETGSIEATSLEQFDRLMNTNV 1498
Query: 130 TSMLCLTSGTLNAFQDSPGLSKT---VVNISSLCALQPYKGWGLYCAGKAARDMLYQVLA 186
S+ LT +P L KT +VN+SS+C L+ + G Y KAA D +A
Sbjct: 1499 RSLYQLT------MLATPELVKTKGNIVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIA 1552
Query: 187 AE--EPSVRVLSYAPGPLDNDMQQ 208
E VRV + PG + D+ +
Sbjct: 1553 LELAPKGVRVNAVNPGVIVTDIHK 1576
>gi|12802725|gb|AAK08072.1|AF325447_1 (AF325447) SDR-like protein [Desulfovibrio gigas]
Length = 270
Score = 60.1 bits (144), Expect = 2e-08
Identities = 77/248 (31%), Positives = 104/248 (41%), Gaps = 36/248 (14%)
Query: 12 VLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAADL 71
VLTGAS G GRALA LA G+ ++++ARS+ L++ K+ L A K+ +A D
Sbjct: 10 VLTGASHGIGRALADALAM---QGANLVLNARSKPPLKEAKKTLEA---GYKIKVAVVD- 62
Query: 72 GTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWAL---- 127
+A R+ A E A TLG + L + W L
Sbjct: 63 -GDAATARVARACVE--------------QAETLGGFAGIIHAAGVLHPGPHLWELDEKQ 107
Query: 128 --NLTSMLCLTSGTLNAFQDSPGLSKT-----VVNISSLCALQPYKGWGLYCAGKAARDM 180
++T C S L A P L + V S A G GLYCA KA +
Sbjct: 108 YDDVTHASCKASWQL-ARAAYPALMRQKDGGLYVLFGSGAASIAMPGIGLYCAAKAFEEH 166
Query: 181 LYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETS--KDPELRSKLQKLKSDGALVDCGTS 238
L + LAAE +V Y PG ++ MQQ ARE + +R+ G L+ S
Sbjct: 167 LMRQLAAETDAVTCFVYQPGKVETRMQQQAREATGGGGEAVRATFTPWHERGELLSAQAS 226
Query: 239 AQKLLGLL 246
A L LL
Sbjct: 227 AVWLARLL 234
>gi|14210648|gb|AAK55494.1| (AY033621) putative short-chain dehydrogenase/reductase Mc1 [Aedes
aegypti]
Length = 254
Score = 59.7 bits (143), Expect = 3e-08
Identities = 57/201 (28%), Positives = 94/201 (46%), Gaps = 20/201 (9%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEE-LGAQQPDLKVVLAA 68
V ++TGAS G G A A L L G+ ++++ R+ L++ E +G Q+P ++L A
Sbjct: 7 VVLITGASSGIGAATAKHLTHL---GATVVMTGRNAESLKKCGAECVGKQKP---LILVA 60
Query: 69 ADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALN 128
E V+ + +++ + + +L+NNA G G + L ++++ N
Sbjct: 61 DVTKQEDNVRVIEETIKKFGKLD-----VLVNNA---GRGVFGSIETTSLDQLDDMLNTN 112
Query: 129 LTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 188
L LT + S G +VN+SS+ L+P+ YC KAA D +V+A E
Sbjct: 113 LRGAYHLTILAVPHLIKSKG---NIVNVSSITGLKPFPNSLAYCISKAALDQFTRVIALE 169
Query: 189 --EPSVRVLSYAPGPLDNDMQ 207
VRV S P + D Q
Sbjct: 170 LAPKQVRVNSVNPAVIATDFQ 190
>gi|14210658|gb|AAK55499.1| (AY033626) putative short-chain dehydrogenase/reductase [Aedes
aegypti]
Length = 254
Score = 59.3 bits (142), Expect = 3e-08
Identities = 57/201 (28%), Positives = 94/201 (46%), Gaps = 20/201 (9%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEE-LGAQQPDLKVVLAA 68
V ++TGAS G G A A L L G+ ++++ R+ L++ E +G Q+P ++L A
Sbjct: 7 VVLITGASSGIGAATAKHLTHL---GATVVMTGRNAESLKKCGAECVGKQKP---LILVA 60
Query: 69 ADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALN 128
E V+ + +++ + + +L+NNA G G + L ++++ N
Sbjct: 61 DVTKPEDNVRVIEETIKKFGKLD-----VLVNNA---GRGVFGSIETTSLDQLDDMLNTN 112
Query: 129 LTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 188
L LT + S G +VN+SS+ L+P+ YC KAA D +V+A E
Sbjct: 113 LRGAYHLTILAVPHLIKSKG---NIVNVSSITGLKPFPNSLAYCISKAALDQFTRVIALE 169
Query: 189 --EPSVRVLSYAPGPLDNDMQ 207
VRV S P + D Q
Sbjct: 170 LAPKQVRVNSVNPAVIATDFQ 190
>gi|15004706|ref|NP_149166.1| Oxidoreductase [Clostridium acetobutylicum]
gi|14994318|gb|AAK76748.1|AE001438_1 (AE001438) Oxidoreductase [Clostridium acetobutylicum]
Length = 251
Score = 57.0 bits (136), Expect = 2e-07
Identities = 56/218 (25%), Positives = 100/218 (45%), Gaps = 19/218 (8%)
Query: 12 VLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAADL 71
V+TGAS G G A A+ G +++ AR L +LK+E+ LKV++ + DL
Sbjct: 8 VITGASSGIGYEAAKAFAK---RGKNLIIIARRREKLEELKKEILHYNRSLKVIVKSIDL 64
Query: 72 GTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNLTS 131
+ V L ++ L+NNA GD SK +N +L +V + +LN+ +
Sbjct: 65 SITSNVYSLYDELKNYNIET------LVNNAG-FGDYSK--VNNQNLEKVESMLSLNIEA 115
Query: 132 MLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE--- 188
++ L+S + ++ G ++NISS +YCA K + LA E
Sbjct: 116 LVILSSLFVRDYEKIEGTQ--LINISSAGGYTIVPNAVIYCATKFFVSSFTEGLARELIE 173
Query: 189 -EPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQK 225
+ +++ AP + + ++A + K+ + + K K
Sbjct: 174 AKSNLKAKVLAPAATETEFGKVASDV-KEYDYQEKFHK 210
>gi|7480271|pir||T29125 ketoacyl reductase homolog - Streptomyces coelicolor
gi|3451448|emb|CAA20507.1| (AL031350) putative dehydrogenase [Streptomyces coelicolor A3(2)]
Length = 276
Score = 56.6 bits (135), Expect = 2e-07
Identities = 67/191 (35%), Positives = 94/191 (49%), Gaps = 15/191 (7%)
Query: 12 VLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAADL 71
++TGAS+G G A A +LA S G+ +++ ARS L L +E+ A ++V + AADL
Sbjct: 10 LVTGASKGLGEAYARELA---SRGAHLVLVARSADALHALADEIRATH-SVRVDVIAADL 65
Query: 72 GTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNLTS 131
QR+L AV L GL LL+NNA +G V G V LA +N+T+
Sbjct: 66 SDRRSPQRVLDAVDGL----GLDVDLLVNNAG-MGAV--GPFLVRPLAPNLQSVDVNVTA 118
Query: 132 MLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE--E 189
++ L L A G +VNI+S A QP Y A KA + +A E
Sbjct: 119 LVGLVH-LLGARMVERG-RGGIVNIASTAAFQPMPYQASYAATKAFVLSFTEAVAEEVRG 176
Query: 190 PSVRVLSYAPG 200
VRV++ PG
Sbjct: 177 TGVRVMAAHPG 187
>gi|11355759|pir||F82378 oxidoreductase, short-chain dehydrogenase/reductase family VCA1108
[imported] - Vibrio cholerae (group O1 strain N16961)
gi|9658554|gb|AAF96999.1| (AE004435) oxidoreductase, short-chain dehydrogenase/reductase
family [Vibrio cholerae]
Length = 265
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/219 (31%), Positives = 105/219 (47%), Gaps = 26/219 (11%)
Query: 12 VLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAADL 71
+LTGAS G G +A LA + G+ +++ AR L L++ L +P+L V+ +ADL
Sbjct: 9 LLTGASGGIGEPIAHTLA---ARGARLILLARDAQKLEALRQSL--PKPELHRVV-SADL 62
Query: 72 GTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWALNLT 130
+EAG+++L + V EL R + QR+ ++INNA T L + V ALNL
Sbjct: 63 TSEAGMEQLQALVEELNRAQ--QRIAVVINNAGT---NQFCLLARRSMESVQRELALNLM 117
Query: 131 SMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE-- 188
+ + + L + P + V+NI S Y G+ YCA KA + + E
Sbjct: 118 TPIQIMHHVLQ-WSRKP---QMVINIGSSLGAIGYPGYASYCAAKAGLHRFSEAMNRELA 173
Query: 189 EPSVRVLSYAPGPLDNDM-----QQLAR---ETSKDPEL 219
++VL AP + + QQL R S +P L
Sbjct: 174 GTGMKVLYLAPRATNTSLNSEAVQQLNRALGNRSDEPSL 212
>gi|7206794|gb|AAF39953.1| (AC006677) Hypothetical protein R05D8.8 [Caenorhabditis elegans]
Length = 279
Score = 55.8 bits (133), Expect = 3e-07
Identities = 58/197 (29%), Positives = 99/197 (49%), Gaps = 17/197 (8%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEE-LGAQQPDLKVVLAA 68
V ++TG+S G GRA A LA+ G+ + ++ R+ L + ++E L + P+ V+ A
Sbjct: 8 VALVTGSSNGIGRATAVLLAQ---EGAKVTITGRNADRLEETRQEILKSGVPEDHVLSIA 64
Query: 69 ADLGTEAGVQRLL-SAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVN-DLAEVNNYWA 126
DL TE G L+ S +++ R + +L+NNA + +G + V+ D++ +
Sbjct: 65 TDLATEKGQDELVNSTIQKFGRLD-----ILVNNAGAAFNDDQGRVGVDQDVSVYDRIMQ 119
Query: 127 LNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCA-LQPYKGWGLYCAGKAARDMLYQVL 185
+N+ S++ LT + G VVN+SS+ A Q + Y KAA D +
Sbjct: 120 INMRSVVTLTQKAKEHLVKAKG---EVVNVSSIGAGPQAQPTFMYYAMSKAALDQYTRSA 176
Query: 186 AAE--EPSVRVLSYAPG 200
A + + VRV S +PG
Sbjct: 177 AIDLIQYGVRVNSVSPG 193
>gi|729325|sp|P39483|DHG2_BACME GLUCOSE 1-DEHYDROGENASE II (GLCDH-II)
gi|2117439|pir||I39853 glucose 1-dehydrogenase (EC 1.1.1.47) 2 - Bacillus megaterium
gi|216270|dbj|BAA14100.1| (D90044) glucose dehydrogenase [Bacillus megaterium]
gi|228658|prf||1808263D glucose dehydrogenase II [Bacillus megaterium]
Length = 261
Score = 55.8 bits (133), Expect = 3e-07
Identities = 57/221 (25%), Positives = 103/221 (45%), Gaps = 21/221 (9%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESM-LRQLKEELGAQQPDLKVVLAA 68
V V+TG S+G GRA+A + + S V S E++ +++ EE G Q ++
Sbjct: 9 VVVVTGGSKGLGRAMAVRFGQEQSKVVVNYRSNEEEALEVKKEIEEAGGQ-----AIIVR 63
Query: 69 ADLGTEAGVQRLL-SAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWAL 127
D+ E V L+ +AV+E + ++INNA V L++ + +V +
Sbjct: 64 GDVTKEEDVVNLVETAVKEFGSLD-----VMINNAGVENPVPSHELSLENWNQVID---T 115
Query: 128 NLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAA 187
NLT + + F ++ + V+N+SS+ + P+ + Y A K ++ + LA
Sbjct: 116 NLTGAFLGSREAIKYFVEN-DIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLAL 174
Query: 188 E--EPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKL 226
E +RV + PG +D + E DPE R+ ++ +
Sbjct: 175 EYAPKGIRVNNIGPGAIDTPINA---EKFADPEQRADVESM 212
>gi|3913463|sp|O17795|DHBX_CAEEL PUTATIVE STEROID DEHYDROGENASE F11A5.12
gi|7498879|pir||T20756 hypothetical protein F11A5.12 - Caenorhabditis elegans
gi|3875767|emb|CAB07363.1| (Z92830) contains similarity to Pfam domain: PF00106 (short chain
dehydrogenase), Score=109.1, E-value=2.7e-29, N=1
[Caenorhabditis elegans]
Length = 315
Score = 55.8 bits (133), Expect = 3e-07
Identities = 49/185 (26%), Positives = 85/185 (45%), Gaps = 14/185 (7%)
Query: 7 GCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVL 66
G + V+TGA+ G G++ + +LAR G + + +R++S L Q K+++ +QPD++V
Sbjct: 46 GASWAVVTGATDGIGKSYSFELAR---RGFNVYIVSRTQSKLEQTKKDILEKQPDIEVRF 102
Query: 67 AAADLGTEA--GVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVN-DLAEVNN 123
A D + ++LLS + E+ +LINN D + +N + + N
Sbjct: 103 ATYDFTNPSVTDYEKLLSKLNEVSVG------ILINNVGMFFDYPEMLHKINGGIDSIAN 156
Query: 124 YWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQ 183
+N L++G L Q + +VNI S + W +Y A K + L
Sbjct: 157 VIIINTLPATLLSAGILP--QMVSRKAGIIVNIGSFAGVVKLAEWSIYSATKKYVEWLTG 214
Query: 184 VLAAE 188
L E
Sbjct: 215 CLRKE 219
>gi|13472648|ref|NP_104215.1| reductase (short chain dehydrogenase or 3-ketoacyl-CoA reductase)
[Mesorhizobium loti]
gi|14023395|dbj|BAB50001.1| (AP003001) short chain dehydrogenase or 3-ketoacyl-CoA reductase
[Mesorhizobium loti]
Length = 248
Score = 55.5 bits (132), Expect = 4e-07
Identities = 57/204 (27%), Positives = 93/204 (44%), Gaps = 22/204 (10%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLV--SARSESMLRQLKEELGAQQPDLKVVLA 67
V ++TGA+RG G +A +LA + G+ ++V + E+ R +KE + A K
Sbjct: 8 VAIVTGAARGIGAGIAKRLA---AEGAAVVVNYATSREAAERTVKEIVAAGG---KATAV 61
Query: 68 AADLGTEAGVQRLLSAVR-ELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWA 126
D+ A V+++ A +P +LINNAAT S G A+ +
Sbjct: 62 QGDVAEAAEVEKMFEAAEIAFGKPS-----ILINNAAT---ASFGTFEEASEADYRRLFD 113
Query: 127 LNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLA 186
N+ + T + F ++ G ++VNI ++ + P LY A KAA D L L+
Sbjct: 114 TNVLGTILTTKAAMRHFPETGG---SIVNIGTISSWNPVPNTSLYSASKAAIDTLTLSLS 170
Query: 187 AE--EPSVRVLSYAPGPLDNDMQQ 208
E ++RV APG +M +
Sbjct: 171 RELGARNIRVNIVAPGYTHTEMTE 194
>gi|12723693|gb|AAK04872.1|AE006311_3 (AE006311) 3-oxoacyl-acyl carrier protein reductase (EC 1.1.1.100)
[Lactococcus lactis subsp. lactis]
Length = 243
Score = 55.1 bits (131), Expect = 6e-07
Identities = 60/209 (28%), Positives = 99/209 (46%), Gaps = 23/209 (11%)
Query: 13 LTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQ--QPDLKVVLAAAD 70
+TG++RG G+A+A Q A+ GS ++++ RS + EEL A+ +K V + D
Sbjct: 10 VTGSTRGIGKAIALQFAK---AGSNLIINGRS-----AISEELLAEFTAYGVKAVGISGD 61
Query: 71 LG-TEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNL 129
+ +E Q + A+ L + +L+NNA D ++ D V +NL
Sbjct: 62 ISKSEDAKQMVAEAIETLGSVD-----ILVNNAGITRDGLSLKMSEEDFESV---LKINL 113
Query: 130 TSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAEE 189
T +T L + S ++NISS+ L G Y A KA L + +A E
Sbjct: 114 TGAFNMTQAVLKPM--TRARSGAIINISSVVGLMGNAGQANYAASKAGLIGLTKSIAREV 171
Query: 190 PS--VRVLSYAPGPLDNDMQQLARETSKD 216
+ VRV + APG +++DM ++ + KD
Sbjct: 172 AARNVRVNAVAPGFIESDMTEVLSDKVKD 200
>gi|13559678|gb|AAK29887.1| (AC024791) Hypothetical protein Y47G6A.22a [Caenorhabditis elegans]
Length = 501
Score = 55.1 bits (131), Expect = 6e-07
Identities = 61/197 (30%), Positives = 96/197 (47%), Gaps = 22/197 (11%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLK-VVLAA 68
V ++TGAS G GRA A LAR + ++ R+ + L +L ++ + D V++ A
Sbjct: 3 VAIVTGASSGIGRAAALLLAR---NNYKLSLTGRNVAALNELAGQIVSAGSDKNDVLVTA 59
Query: 69 ADLGTEAGVQRLLSA-VRELPRPEGLQRLLLINNAATL--GDVSKGFLNVNDLAEVNNYW 125
+L +E + ++ A V++ R + LIN+A L G V + V D E+ N
Sbjct: 60 VELASEEAPKTIVDATVQKFGRID-----TLINSAGILRAGPVLDSGIEVYD--ELMN-- 110
Query: 126 ALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVL 185
+N+ S++ LT L + G TVVN+SS+ P+ YC K+A D + L
Sbjct: 111 -VNVRSLIRLTRAALPHIITTKG---TVVNVSSINGPCPFPNVTYYCMSKSAVDQFTKCL 166
Query: 186 AAEEP--SVRVLSYAPG 200
A E VRV + PG
Sbjct: 167 ALEMAPNGVRVNAVCPG 183
Score = 38.5 bits (88), Expect = 0.061
Identities = 37/106 (34%), Positives = 51/106 (47%), Gaps = 12/106 (11%)
Query: 99 INNAATL--GDVSKGFLNVNDLAEVNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNI 156
IN+A L G V + V D E+ N +N+ S++ LT L + G TVVN+
Sbjct: 381 INSAGILRAGPVLDSGIEVYD--ELMN---VNVRSLIRLTRAALPHIITTKG---TVVNV 432
Query: 157 SSLCALQPYKGWGLYCAGKAARDMLYQVLAAEEP--SVRVLSYAPG 200
SS+ P+ G YC K+A D + LA E VRV + PG
Sbjct: 433 SSINGPCPFAGVTYYCMSKSAVDQFTKCLALEMAPNGVRVNAVCPG 478
>gi|3913475|sp|Q17703|DHBV_CAEEL PUTATIVE STEROID DEHYDROGENASE C06B3.4
gi|7495502|pir||T18980 hypothetical protein C06B3.4 - Caenorhabditis elegans
gi|3874045|emb|CAB01114.1| (Z77652) contains similarity to Pfam domain: PF00106 (short chain
dehydrogenase), Score=107.8, E-value=6.7e-29, N=1
[Caenorhabditis elegans]
Length = 314
Score = 54.7 bits (130), Expect = 8e-07
Identities = 46/172 (26%), Positives = 81/172 (46%), Gaps = 14/172 (8%)
Query: 7 GCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVL 66
G + V+TGA+ G G++ + +LA+ G + + +R++S L K+E+ PD++V
Sbjct: 46 GASWAVVTGATDGIGKSYSFELAK---RGFNVYIVSRTQSKLEHTKKEILEVHPDIEVRF 102
Query: 67 AAADLG--TEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVN-DLAEVNN 123
A D + + ++LLS + E+ +LINN D + +N + + N
Sbjct: 103 ATFDFTNPSVSDYEKLLSKLNEVSIG------ILINNVGMFFDYPEMLHKINGGIDSIAN 156
Query: 124 YWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGK 175
+N L++G L Q P + +VNI S+ L W +Y A K
Sbjct: 157 VTIINTLPATLLSAGILP--QMVPRKAGIIVNIGSVAGLATMAEWSVYSATK 206
>gi|7495127|pir||T18829 hypothetical protein C01G12.5 - Caenorhabditis elegans
gi|3873882|emb|CAB03815.1| (Z81457) contains similarity to Pfam domain: PF00106 (short chain
dehydrogenase), Score=200.8, E-value=6.9e-57, N=1;
PF00678 (Short chain dehydrogenase/reductase
C-terminus), Score=16.0, E-value=0.0029, N=1
[Caenorhabditis elegans]
Length = 279
Score = 54.3 bits (129), Expect = 9e-07
Identities = 58/199 (29%), Positives = 100/199 (50%), Gaps = 17/199 (8%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEE-LGAQQPDLKVVLAA 68
V ++TG+S G GRA A LAR G+ + ++ R+ L + K+E L + P+ V+
Sbjct: 8 VALVTGSSNGIGRATAILLAR---EGAKVTITGRNAQRLEETKQEILRSGVPEDHVLSII 64
Query: 69 ADLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNV-NDLAEVNNYWA 126
ADL TE+G L+++ ++ RL +L+NNA +G + V +++ +
Sbjct: 65 ADLATESGQIELMNSTVDI-----FGRLDILVNNAGAAITDLEGHIGVGTNVSVFDKTMR 119
Query: 127 LNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCA-GKAARDMLYQVL 185
+NL S++ LT + G +VN+SS+ Q + +Y A K+A D +
Sbjct: 120 INLRSVVTLTQKAKEHLIKTKG---EIVNVSSIAGGQHAQPELIYYAMSKSALDQYTRSA 176
Query: 186 AAE--EPSVRVLSYAPGPL 202
A + + VRV S +PG +
Sbjct: 177 AIDLIQHGVRVNSVSPGDI 195
>gi|13559679|gb|AAK29888.1| (AC024791) Hypothetical protein Y47G6A.22b [Caenorhabditis elegans]
Length = 206
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/197 (31%), Positives = 97/197 (48%), Gaps = 22/197 (11%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLK-VVLAA 68
V ++TGAS G GRA A LAR + ++ R+ + L +L ++ + D V++ A
Sbjct: 3 VAIVTGASSGIGRAAALLLAR---NNYKLSLTGRNVAALNELAGQIVSAGSDKNDVLVTA 59
Query: 69 ADLGTEAGVQRLLSA-VRELPRPEGLQRLLLINNAATL--GDVSKGFLNVNDLAEVNNYW 125
+L +E + ++ A V++ R + LIN+A L G V + V D E+ N
Sbjct: 60 VELASEEAPKTIVDATVQKFGRID-----TLINSAGILRAGPVLDSGIEVYD--ELMN-- 110
Query: 126 ALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVL 185
+N+ S++ LT L + G TVVN+SS+ P+ G YC K+A D + L
Sbjct: 111 -VNVRSLIRLTRAALPHIITTKG---TVVNVSSINGPCPFAGVTYYCMSKSAVDQFTKCL 166
Query: 186 AAEEP--SVRVLSYAPG 200
A E VRV + PG
Sbjct: 167 ALEMAPNGVRVNAVCPG 183
>gi|15228524|ref|NP_186983.1| unknown protein [Arabidopsis thaliana]
gi|6017123|gb|AAF01606.1|AC009895_27 (AC009895) unknown protein [Arabidopsis thaliana]
Length = 345
Score = 53.9 bits (128), Expect = 1e-06
Identities = 67/227 (29%), Positives = 102/227 (44%), Gaps = 36/227 (15%)
Query: 13 LTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEEL-GAQQP-DLKVVLAAAD 70
+TGASRG G LA Q A L + +++SAR+++ L ++K EL G P D+KV+
Sbjct: 48 ITGASRGIGEILAKQFASL---DAKLILSARNKAELDRVKSELKGKFAPEDVKVLPLDLA 104
Query: 71 LGTEAGVQRLLSAVRELPRPEGLQRLLLINNAA------TLGDVSKGFLNVNDLAEVNNY 124
G E+ + AV P G L++NAA D S+ L +VN +
Sbjct: 105 SGEESLKHVVEQAVSLFP---GAGVDYLVHNAAFERPKSKASDASEETLKTT--FDVNVF 159
Query: 125 WALNLTSMLCLTSGTLNAFQDSPGLSKT----VVNISSLCALQPYKGWGLYCAGKAARDM 180
++LT ++ +P + K V ISS P G +Y A K A
Sbjct: 160 GTISLTKLV------------APHMLKQGGGHFVVISSAAGKVPSPGQAIYSASKHALHG 207
Query: 181 LYQVLAAE--EPSVRVLSYAPGPLD--NDMQQLARETSKDPELRSKL 223
+ L +E + ++V PGP++ N E SK PEL ++L
Sbjct: 208 YFHSLRSEFCQKGIKVTVVCPGPIETWNGTGTSTSEDSKSPELLAQL 254
>gi|2425123|gb|AAB70845.1| (AF019986) PksB [Dictyostelium discoideum]
Length = 260
Score = 53.5 bits (127), Expect = 2e-06
Identities = 54/202 (26%), Positives = 98/202 (47%), Gaps = 20/202 (9%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69
+ ++TGAS G G + A + G+ +++ R L +L+++L A KV+
Sbjct: 9 IVLITGASSGIGESCAKIFHQ---NGNHIILCGRRVDRLNKLRDQLIANNSGGKVLACQV 65
Query: 70 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAA-TLGDVSKGFLNV-NDLAEVNNYWA 126
D+ + + ++++ + PE ++ + +LINNA +LG S ++ NDL V +
Sbjct: 66 DVSSMESIDKMINEL-----PEDMKSIDILINNAGLSLGMDSVSEIDAKNDLDSVID--- 117
Query: 127 LNLTSMLCLTSGTL-NAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVL 185
N+ + +T L N Q + G + N+SS+ Y +YCA KAA + VL
Sbjct: 118 TNVKGVFRVTRKILPNMIQRNSGY---IFNVSSIAGSMFYPNGSIYCASKAAVNAFSDVL 174
Query: 186 AAEEPS--VRVLSYAPGPLDND 205
E S +RV + PG ++ +
Sbjct: 175 RKEVVSTKIRVTNVCPGLVETE 196
>gi|11250506|pir||D82842 oxidoreductase XF0145 [imported] - Xylella fastidiosa (strain
9a5c)
gi|9104934|gb|AAF82958.1|AE003868_4 (AE003868) oxidoreductase [Xylella fastidiosa 9a5c]
Length = 251
Score = 53.5 bits (127), Expect = 2e-06
Identities = 55/191 (28%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 12 VLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAADL 71
++TGA+ GFGRA + R + G ++ + R L E L A+ P + + A D+
Sbjct: 6 LITGATSGFGRA---AVHRFANAGWRVIATGRRIERL----EALAAEWPPGHIHITAFDM 58
Query: 72 GTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNLTS 131
A L +A++ LP +L+ N LG DLA+ N+TS
Sbjct: 59 RDSA---TLHTAIQTLPADFADIDVLVNNAGLALGTAPAQH---TDLAQWREMIDTNITS 112
Query: 132 MLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE--E 189
++ LT L + G+ ++NISS+ A PY G +Y KA L ++
Sbjct: 113 LVTLTHHLLPTLIERKGM---IINISSVAATYPYTGGNVYAGTKAFVKQFSLGLRSDLHG 169
Query: 190 PSVRVLSYAPG 200
VRV S PG
Sbjct: 170 TGVRVTSIEPG 180
>gi|7296705|gb|AAF51984.1| (AE003602) CG12171 gene product [Drosophila melanogaster]
Length = 257
Score = 53.5 bits (127), Expect = 2e-06
Identities = 61/206 (29%), Positives = 100/206 (47%), Gaps = 26/206 (12%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQ--QPDLKVVLA 67
V ++TGAS G G + LA+L G ++ + R+ L + E++ A P L+V
Sbjct: 8 VIIVTGASSGIGAGTSVLLAKL---GGLLTIVGRNLDKLNETAEQIVAAGGAPALQV--- 61
Query: 68 AADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWAL 127
AAD+ +E+ VQ ++SA L + + +L+NNA L G + L + +
Sbjct: 62 AADINSESDVQGIVSAT--LAKHGRID--VLVNNAGIL---ELGSIENTSLEQFDRVMNT 114
Query: 128 NLTSMLCLTSGTLNAFQDSPGLSKT---VVNISSLCALQPYKGWGLYCAGKAARDMLYQV 184
N+ S+ LT +P L KT +VN+SS+ ++ + G Y KAA D +
Sbjct: 115 NVRSLYQLTHLV------TPELIKTKGNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRC 168
Query: 185 LAAE--EPSVRVLSYAPGPLDNDMQQ 208
+A E VRV S PG + ++Q+
Sbjct: 169 VALELAPKGVRVNSVNPGVIITELQR 194
>gi|729324|sp|P39482|DHG1_BACME GLUCOSE 1-DEHYDROGENASE I (GLCDH-I)
gi|80112|pir||JS0385 glucose 1-dehydrogenase (EC 1.1.1.47) - Bacillus megaterium
gi|216268|dbj|BAA14099.1| (D90043) glucose dehydrogenase [Bacillus megaterium]
gi|228657|prf||1808263C glucose dehydrogenase I [Bacillus megaterium]
Length = 261
Score = 53.1 bits (126), Expect = 2e-06
Identities = 56/225 (24%), Positives = 110/225 (48%), Gaps = 29/225 (12%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSE-----SMLRQLKEELGAQQPDLKV 64
V V+TG+S G G+A+A R + + ++V+ RS+ S+L ++K+ G +
Sbjct: 9 VVVITGSSTGLGKAMA---IRFATEKAKVVVNYRSKEEEANSVLEEIKKVGG------EA 59
Query: 65 VLAAADLGTEAGVQRLL-SAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNN 123
+ D+ E+ V L+ S+++E + + ++INNA VS ++++D +V +
Sbjct: 60 IAVKGDVTVESDVINLVQSSIKEFGKLD-----VMINNAGMENPVSSHEMSLSDWNKVID 114
Query: 124 YWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQ 183
NLT + + F ++ + TV+N+SS+ P+ + Y A K ++ +
Sbjct: 115 ---TNLTGAFLGSREAIKYFVEN-DIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTE 170
Query: 184 VLAAE--EPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKL 226
LA E +RV + PG ++ + E DPE R+ ++ +
Sbjct: 171 TLALEYAPKGIRVNNIGPGAINTPINA---EKFADPEQRADVESM 212
>gi|3913470|sp|O57314|DHBX_ANAPL PUTATIVE STEROID DEHYDROGENASE SPM2
gi|2665393|dbj|BAA23765.1| (AB009304) steroid dehydrogenase [Anas platyrhynchos]
Length = 312
Score = 53.1 bits (126), Expect = 2e-06
Identities = 64/220 (29%), Positives = 105/220 (47%), Gaps = 23/220 (10%)
Query: 5 GLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKV 64
GLG A V+TGA+ G G+A A +LA+ G + + +RS+ L Q+ E+ +Q ++
Sbjct: 46 GLG-AWAVVTGATDGIGKAYAKELAK---RGMKVALISRSKEKLDQVAGEI-TEQYGVET 100
Query: 65 VLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAE-VNN 123
+ AD G + + A EGL+ +L+NN + F++V DL + ++
Sbjct: 101 KVIVADFGEREDIYDRIRA-----GLEGLEIGVLVNNVGISYSYPEYFIDVPDLDKTIDK 155
Query: 124 YWALNLTSMLCLTSGTLNAFQDSPGL---SKTVV-NISSLCALQPYKGWGLYCAGKAARD 179
+N+ S+ +T L PG+ SK V+ NISS + P LY A KA D
Sbjct: 156 MININIMSVCKMTRLVL------PGMLERSKGVILNISSAAGMYPTPLLTLYSASKAFVD 209
Query: 180 MLYQVLAAEEPS--VRVLSYAPGPLDNDMQQLARETSKDP 217
+ L AE S + V S P + M ++++ + P
Sbjct: 210 YFSRGLHAEYKSKGIIVQSVMPYYVATKMSKISKPSFDKP 249
>gi|7206785|gb|AAF39944.1| (AC006677) Hypothetical protein R05D8.9 [Caenorhabditis elegans]
Length = 281
Score = 53.1 bits (126), Expect = 2e-06
Identities = 54/196 (27%), Positives = 94/196 (47%), Gaps = 15/196 (7%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEE-LGAQQPDLKVVLAA 68
V ++TG+S G GRA A A+ G+ + V+ R+ L + ++E L + P+ V+ A
Sbjct: 9 VALVTGSSNGIGRAAAVLFAK---DGAKVTVTGRNAERLEETRQEILKSGVPESHVLSVA 65
Query: 69 ADLGTEAGVQRLL-SAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVN-DLAEVNNYWA 126
DL E G L+ S +++ R + +L+NNA + +G + V+ D++ +
Sbjct: 66 TDLAAEKGQDELVNSTIQKFGRLD-----ILVNNAGAAFNDDQGRVGVDQDVSVYDKIMQ 120
Query: 127 LNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLA 186
+N+ S++ LT + G V +I+ QP G Y K+A D + A
Sbjct: 121 INMRSVVTLTQKAKEHLVKAKGEIVNVSSIAGTAHAQP--GVMYYAMSKSALDQFTRCAA 178
Query: 187 AE--EPSVRVLSYAPG 200
+ + VRV S +PG
Sbjct: 179 IDLIQYGVRVNSVSPG 194
>gi|15235621|ref|NP_193054.1| short-chain alcohol dehydrogenase like protein [Arabidopsis
thaliana]
gi|7430994|pir||T07698 short-chain alcohol dehydrogenase homolog F17N18.70 - Arabidopsis
thaliana
gi|4753652|emb|CAB41928.1| (AL049751) short-chain alcohol dehydrogenase like protein
[Arabidopsis thaliana]
gi|7268020|emb|CAB78360.1| (AL161535) short-chain alcohol dehydrogenase like protein
[Arabidopsis thaliana]
Length = 263
Score = 53.1 bits (126), Expect = 2e-06
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 12/200 (6%)
Query: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69
V ++TGA+RG GR +A L L + ++ VS+ S++ L L EL + A
Sbjct: 17 VAIVTGATRGMGREIAIHLHSLGARVTINYVSSSSKAEL--LVSELNDSSQLKSAIAVKA 74
Query: 70 DLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNL 129
D+ + L + E ++ ++ N A + D L+ L + +N + +N
Sbjct: 75 DVSDPDQINNLFDQTEQ----EFGSKVHIVVNCAGVLDPKYPSLSETTLEDFDNTFTINT 130
Query: 130 T-SMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 188
S LC + G +++ S + L P G+G+Y A KAA + + +VLA E
Sbjct: 131 RGSFLCCKEAAKRVMRGGGG-RIIMMSTSMVGGLAP--GYGVYAASKAAVETMVKVLAKE 187
Query: 189 EPSVRVLS--YAPGPLDNDM 206
R+ + APGP+ +M
Sbjct: 188 LKGSRITANCVAPGPVATEM 207
Database: nr
Posted date: Aug 30, 2001 8:41 AM
Number of letters in database: 238,720,434
Number of sequences in database: 750,607
Lambda K H
0.317 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 112,917,875
Number of Sequences: 750607
Number of extensions: 4230858
Number of successful extensions: 13594
Number of sequences better than 10.0: 851
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 787
Number of HSP's that attempted gapping in prelim test: 13226
Number of HSP's gapped (non-prelim): 882
length of query: 261
length of database: 238,720,434
effective HSP length: 117
effective length of query: 144
effective length of database: 150,899,415
effective search space: 21729515760
effective search space used: 21729515760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
